Quote Originally Posted by king6
Are you thinking of the pill? Cause the topical just prevents DHT from binding to the androgen receptor. It wont get in your bloodstream.
No, not talking about the pill. Spironolactone by nature is quite lipophylic & easily absorbed through the skin, especially scalp skin. This is magnified when it is is used with certain ingredients such as those used in Dr Lee's spironolactone liquid. There were a couple of guys on the Men's health board on Meso-rx who tested his product with before & after blood tests. They found it rapidly lowered test levels & increased estrogen levels. I don't doubt this at all, even if there are a few studies around showing no systemic effects from topical spiro.