which AS use the same receptors?

[adude006]

Anyone have any list or something on which steroids use the same cell receptors and which use different ones. Tried searching on goggle too but no luck.

Also, which steroids fall under the receptor in***endent category?

[vitor]

Those most commen aas with most of their activity at the Androgen recepter are:
-Trenbolone
-Deca
-Primo
-Testosterone(also has non-AR meditaded actitivity)
-Eq
-Masteron
-Anavar

D-bol, drol, halo, winstrol and t-bol all bind weakly to the AR.

[hugovsilva]

The are not different receptors for each steroid. What happens is that they have different affinities for the AR.

[Property of Steroid.com]

They bind with different strengths at the AR, but when you look at their ability to promote gene transcription at different regions, you'll find that even the weakly binding steroids have the ability to promote very strong site specific gene transcription in different places, even without strong AR binding.

[Cutler fan]

The are not different receptors for each steroid. What happens is that they have different affinities for the AR.

Agree. Why this stupid issue ( different receptors) is so common.

[adude006]

After a 3-4 month cycle are there ways to speed up the receptor recovery rather than waiting it out naturally?

[dale]

After a 3-4 month cycle are there ways to speed up the receptor recovery rather than waiting it out naturally?

correct me if i'm wrong (i'm sure someone will)...doesn't benedryl help in this situation?

[hugovsilva]

What a confusion.
Benadryl has nothing to do with with the AR (unless there are new studies about it). Benadryl upgrades the beta2 receptors.
As for AR downgrading, I am not to what extent it happens, but I remeber reading that estrogen helps upgrading them and androgens increase the number of AR's. Your gains start decrease along the cycle because of a process named "homeostasis", which means the body, trying to find balance, increases the secretion of catabolic hormones to counteract the effect of the anabolics.

[Atomini]

correct me if i'm wrong (i'm sure someone will)...doesn't benedryl help in this situation?

No, because Benadryl upregulates the Bea 2 receptors on FAT tissue, not muscle tissue. Fat cell receptors are way different than muscle cell receptors. Benadryl is used while using Clenbuterol or Ephedrine (drugs that bind to the Beta-2 receptor to initiate fat metabolism). Those drugs cause downregulation of those receptors, and Benadryl can upregulate them.

[Pooks]

As for AR downgrading, I am not to what extent it happens, but I remeber reading that estrogen helps upgrading them and androgens increase the number of AR's. Your gains start decrease along the cycle because of a process named "homeostasis",

There are probably many ways the body finds homeostasis, but one way it does is thru the SHBG.
High levels of SHBG will tie up free testosterone rendering it useless.
Elevated levels of Estrogen increase the levels of SHBG.

Woman have higher levels of SHBG.. as do older man... that could explain why Testosterone has less effect on those two groups.

"Binds up to 98 percent of the steroid hormones in the blood including 5a-dihydrotestosterone (DHT), testosterone and androstenediol with particularly high affinity, and estradiol and estrone with slightly lower affinity"

"Male and female children have similar SHBG concentrations until the onset of puberty, when SHBG levels begin decreasing more rapidly in males than in females.
• Levels are lower in men than in women, due to the higher ratio of estrogens to androgens in women."

"True androgen status can be assessed either by measuring free testosterone or by calculating the ratio of total testosterone to SHBG, known as the free androgen index (FAI)."

[Property of Steroid.com]

What a confusion.
Benadryl has nothing to do with with the AR (unless there are new studies about it). Benadryl upgrades the beta2 receptors.
As for AR downgrading, I am not to what extent it happens, but I remeber reading that estrogen helps upgrading them and androgens increase the number of AR's. Your gains start decrease along the cycle because of a process named "homeostasis", which means the body, trying to find balance, increases the secretion of catabolic hormones to counteract the effect of the anabolics.

I've been thinking about that fact for awhile now. Nicotine increases the amount of Nicotine receptors in your brain...so the first time you smoke a cigarette, there's not many receptors there, and you get a buzz from the amount of nicotine vs/ the amount of receptors...they're literally saturated with nicotine. Now, when you keep smoking, you need to smoke more and more to get that feeling, because you have more receptors and the amount of nicotine vs/ receptor is getting less (in a relative fashion).

Maybe it's similar with steroids...you know what I mean...we think it's all good and that having all of these functioning receptors increasing in number from our androgen use is a good thing, but maybe the ratio of receptor to androgen is the important thing here, and that's why we use more steroids, and after a point, they become less effective...because logically more receptors would mean we'd likely need to use less...but it's not that way...

So maybe the ratio is important?

[Pooks]

I've been thinking about that fact for awhile now. Nicotine increases the amount of Nicotine receptors in your brain...so the first time you smoke a cigarette, there's not many receptors there, and you get a buzz from the amount of nicotine vs/ the amount of receptors...they're literally saturated with nicotine. Now, when you keep smoking, you need to smoke more and more to get that feeling, because you have more receptors and the amount of nicotine vs/ receptor is getting less (in a relative fashion).

Maybe it's similar with steroids...you know what I mean...we think it's all good and that having all of these functioning receptors increasing in number from our androgen use is a good thing, but maybe the ratio of receptor to androgen is the important thing here, and that's why we use more steroids, and after a point, they become less effective...because logically more receptors would mean we'd likely need to use less...but it's not that way...

So maybe the ratio is important?

hmmm interesting thought Mr. Roberts.
so we can tolerate more nicotine or steroids as we gain more receptors.
To get the F'ed Up feeling (dizziness) we need to raise the dosages..
not sure what the F'ed up feelings of TEST are... the test flu?...

Ummm.. question is does this makes steroids less potent.. or are we just able to handle higher doses, and better gains without getting sick...

[hugovsilva]

I've been thinking about that fact for awhile now. Nicotine increases the amount of Nicotine receptors in your brain...so the first time you smoke a cigarette, there's not many receptors there, and you get a buzz from the amount of nicotine vs/ the amount of receptors...they're literally saturated with nicotine. Now, when you keep smoking, you need to smoke more and more to get that feeling, because you have more receptors and the amount of nicotine vs/ receptor is getting less (in a relative fashion).

Maybe it's similar with steroids...you know what I mean...we think it's all good and that having all of these functioning receptors increasing in number from our androgen use is a good thing, but maybe the ratio of receptor to androgen is the important thing here, and that's why we use more steroids, and after a point, they become less effective...because logically more receptors would mean we'd likely need to use less...but it's not that way...

So maybe the ratio is important?

Makes sense.

Maybe it is not so much about the number of AR's that get activated and more about the % that gets activated.

Interesting thought.