An effective dose of Letrozole (Femara) is .25-.5mg/day (I use .25mgs/day), but be forewarned, if you go over that amount, it can kill your sex drive. Also worth noting is that there´s a rebound effect on your estrogen when you come off Letrozol. Maximum inhibition of the aromatase enzyme has been found to happen at doses as low as 100mcg! (2)

Hey Duramax, that doesn't sound very good - although the positives are great, the negatives are everything that I'm not interested in.
Is it oral?