I dont see why you cant be on it indefinatly, it just advises against taking it ED, strongly advises for that matter. I can back them up on that I wouldnt want to take it ED because the pump would probably cause you to pop into a fleshy mess. It is kinda scary how goo it works, I would like to try some AMP02 as Ive heard good things about it but I dont see how it can come close to this stuff TBH.