Just something I found.. May or may not be relevant..

"ARIMIDEX should not be taken with tamoxifen or estrogen-containing therapies"

http://www.arimidex-us.com/index.aspx


"At a median follow-up of 33 months, the combination of ARIMIDEX and tamoxifen did not demonstrate any efficacy benefit when compared with tamoxifen in all patients as well as in the hormone receptor-positive subpopulation. This treatment arm was discontinued from the trial. Based on clinical and pharmacokinetic results from the ATAC trial, tamoxifen should not be administrated with anastrozole."

It further states that,

"Co-administration of anastrozole and tamoxifen resulted in a reduction of anastrozole plasma levels by 27% compared with those achieved with anastozole alone. Estrogen containing therapies should not be used with ARIMIDEX as they may diminish pharmacologic action."

http://www1.astrazeneca-us.com/pi/arimidex.pdf


In my opinion Aromasin should be used instead of Arimidex (L-dex), the only major problems being it's super expensive price and unavailability to the non-prescribed users..