Research has shown that Estrogen increases the mitogen activated protein kinase cascade, localized IGF-1, and an increase in system growth hormone levels.
The protein kinase cascade is an important reaction for IGF-1 and insulin to cause their anabolic effect. The raising of Growth hormone as a result of estrogen, also plays a synergistic role with testosterone and other anabolic hormones. Estrogen also helps in the process of retaining water, which can help cell volumization and ultimately leads to increased protein synthesis.
So you need some estrogen in the body to help you grow.
And yes to the last part of your statement, thats what I said. Letro is only recommended if you have a history of gyno and that your are sensitive to estrogen levels.
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