
Originally Posted by
Swifto
Toremifene is my favourite and should be a part of EVERYONES PCT. It drastically raises LH, FSH, T. Has been shown to increase bone density and lipids too. Its not carried by the sponsor here, though, therfore its a bit tricky.
As for Clomid vs. Tamox, I prefer Clomid and think its better than Tamox for HPTA restoration. Low dose that is. There is far more research done on Clomid on hypogondal males on Clomid and its testosterone raising effects. There are even extended studies done on Clomid, lasting almost 12 months, if my memory serves correct. With no lasting sides.
It seems Clomid's vision disturbances are temporary and Tamox's are not. Tamox is a also a proven carcinogen.
I also recently read a study that stated Tamox DID NOT raise LH in individuals, the same cannot be said about Clomid. I cant find the study though, been searching for it the last 4 days.
EDIT: Just found the ****er:
Int J Androl. 1992 Feb;15(1):14-8.Links
Comment in:
Int J Androl. 1992 Dec;15(6):507-8.
Treatment of idiopathic oligozoospermia with tamoxifen--a randomized controlled study.Krause W, Holland-Moritz H, Schramm P.
Department of Andrology, Philipps-Universitat, Marburg, Germany.
There is no conclusive evidence of the usefulness of tamoxifen in the treatment of idiopathic oligozoospermia (OAT-syndrome), as it has been used mostly in uncontrolled studies. We herein report on the controlled treatment of OAT-syndrome with tamoxifen versus placebo following a randomized design. Seventy-six men with sperm counts of 2-20 x 10(6) ml-1, sperm motility of 20-50%, and sperm morphology (abnormal cells) between 50 and 80% were involved in the study. Patients with varicocele, a history of testicular maldescent or genital inflammation were excluded. Thirty-nine patients received tamoxifen (30 mg daily), 37 patients placebo. There was a statistically significant increase in the mean serum testosterone level after treatment in the tamoxifen-treated group (from 4.9 +/- 1.9 to 7.9 +/- 3.6 ng ml-1) in comparison to the placebo group (5.3 +/- 2.0 and 5.6 +/- 2.0 ng ml-1). Serum FSH levels increased slightly in the tamoxifen group (from 6.8 +/- 4.1 to 7.3 +/- 4.8 mU ml-1), but this was not statistically significant in comparison to the placebo group (from 5.9 +/- 3.9 to 5.2 +/- 3.5 mU ml-1). Serum levels of LH did not show any differences between groups. The sperm count increased during treatment from 9.3 +/- 11.7 to 11.4 +/- 13.7 x 10(6) ml-1 in the tamoxifen group and from 9.1 +/- 7.1 to 9.3 +/- 8.8 x 10(6) ml-1 in the placebo group; this difference did not reach statistical significance. The percentage of motile and abnormal sperm was not different between the two treatment groups.
Toremifene should be the backbone of ones PCT, with either low dose Clomid (my choice) or Tamox.