I find chromium (polynicotinate w/ preference) to be superior to ALA. Vanadium is also effective... but there are concerns w/ regard to its toxicity which cannot be absolutely dismissed IMO.
To date, I've seen no toxicity reports on chromium polynicotinate... and only one of significance w/ regard to chromium picolinate (and THAT animal study used an INSANE amount of chromium per kg).
While chromium is a mainstay for myself and my clients, I do believe a combination of GDAs to be more effective than any one GDA... so I often make suggestions where that is concerned.
Of the 3 mentioned above, I'd say that a low dose of vanadium + a relatively moderate dose of chromium, is superior to either one taken alone.
However, I'm not comfortable suggesting the long-term use of vanadium... as per my statements above.
Chromium however, I use year-round.









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