Quote Originally Posted by Dog-Slime View Post
Swifto I got a question for you. I realize this probably hasn't been studied so you prob dont have the answer but I figured if anyone knew you prob would... Do any SERMS act as agonist on the AR? I have heard that estrogen can upregulate the ar so this would be very useful if one of them did.
Thats a very good question.

SERMs such as Rolaxifene, can exert apoptosis in androgen-responsive human cells (prostate). But do so in an androgen independant manner (neither up regulation/down regulation of the AR).

I'm going to come back to this as its 10.47pm here and its been a long day.