If you do the letro reversal make sure you run nolva at least two weeks after last letro dose to keep estrogen rebound from binding to gyno receptors. Gyno is weird, it can seem puffy one minute but then if you go out in the cold or something the nipple recesses back in and looks normal. I had gyno 4 years ago and letro reversal diddnt work for me and I went under the knife. Hope this helps.