if thats the case then you need to do some actuall resurch cus 2 weeks on 2 weeks off is the most effective way ive used clen and ive tryed up to 12 weeks before consecutivley using ketofen.....the longer you run clen the less effective it becomes due to receptor down-regulation....the best way to cleans the receptors is time off imho....obviously its different for everyone but i think youll find a lot of peeps would agree....