I got this post from elite thought you would like some more info on this subject.

Some folks do find that one week on clen, one week on eca works better for them, but the main point is that the two day on, two day off is NOT the way to take clen. And by then end of 8 weeks, you will need a break from both the clen and the eca.

One other point of interest would be adding in the Yohim. Take a look at some of he threads by Macro on this.

I just got to chuckle at all you "less than 50mcg" T3 folks. My guinea pigs START at 50mcg and quickly ramp up. Then take a LONG time to comedown. The taper down is the most important part - you must give your body enough time to re-start normal production.
We let them ramp up based on how they are effected - I let them decide... we increase the dose every three days until they hit a dose where they feel "uncomfortable". We then back off 25mcgs and then hold at that level for a good six days, then start the tapering back down.

Each respond differently to the dosage, and adding in eca/clen will also come into play. Some top out quick at 125/150, while I have gone to 250. And I've not really seen to much difference from men or women - as in it don't seem to matter how big or small you are. But this is just anecdotal observations.

If you tilt you head to the right, you will see my attempt to make a graph of a typical dosing schedule. Each dot is 12.5mcgs of T3 and the interval is three days. This is an 8 week cycle where we jump in with both feet, ramp up quick, hold, then back off with a nice long taper

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So on day one you would take four 12.5mcg doses of T3 every day. Now I like to spread the dose out. But I don’t think it really matters much if you were to take 25mcg in the morning and 25mcg in the afternoon. In other words, it’s not a big deal to take four SEPERATE12.5mcg doses (no fan of cutting tabs). After three days, you would go to 75mcg, Say 25 in the morning, 25 in the afternoon, and 25 in the evening.

And notice the LONG tapper back down. This is key.

I also like to make the anabolic used during the cycle longer than the T3/eca/clen cycle to prevent as much muscle loss as possible. So start one week prior to the T3 and keep on one week after. This would give you a 10 week total cycle for cutting.

Now “uncomfortable” is not the most scientific term LOL, but you WILL know it. Shaky, skidish, like you just pounded a 12 of Mt Dew.... And about the dosing schedule, I suggest one takes it through out the day. From all accounts, you just can't say take "x" amount of T3 and you will get "x" results. If you find that taking it on an empty stomach means you use less while getting the same effect, then hell, by all means take it on an empty gut. Myself, and a few others seem to do better if it don't kick in quite as fast, so I take it with food. But again - that’s just me.

I've posted this so many times that I almost have given up, if anyone can show me proof that over doing T3 kills your thyroid.... (Yes, while your 'on' T3 it shuts down) but your thyroid WILL START BACK UP and if you do a solid slow taper, you can avoid the rebound.