Probably one of the most important anti-aging medicines a person can take in my opinion. My TRT Doc added this compound to my DHEA/Pregnenolone cream and I can tell you first hand the huge positive affect it has on me. Mild feelings of a wonderful uphoria (just feel damn good all the time), biig increase in libido and neuro protection.
Deprenyl reduces the age-related decline of dopamine, increasing its availability to preserve youthful brain activity
Deprenyl was originally developed as a ‘psychic energizer’, designed to integrate some amphetamine-like brain effects with anti-depressant effects. It has since been shown to protect nerve cells against a wide, and growing, number of neurotoxins, and has been shown to be a neuroprotection/neurorescue agent when nerve cells are exposed to damaging or stressful conditions.
Extending life-expectancy
Professor Joseph Knoll proved that Deprenyl improves the availability of dopamine, slows its age-related decline and helps maintain healthy brain cells by acting as a selective MAO-B inhibitor.
Professor Knoll emphasized that the nigrostriatal tract, the tiny DA-using nerve cluster in the basal ganglia (‘old brain’), typically dies off at an average rate of 13% per decade starting around age 45 in humans. This fact sets the human lifespan at about 115 years, since by that age the nigral neuron population would have dropped below 10% of its original number, at which time death ensues even if in all other respects the organism were healthy.
Therefore, human longevity is in-part governed by the rate of dopamine decline. Its support and enhancement means not only longer life, but lucid mental capabilities too. In fact, four different rat studies and one dog study have shown Deprenyl to be an effective life-extension agent.
Based on the sum total of research, Knoll has suggested that if Deprenyl were used from the 40s on, and only modestly lowered the nigrostriatal neuron death rate – say, from 13% to 10% per decade – then the average human lifespan might increase by 15 years.
Other uses
Deprenyl has become a standard treatment for Parkinson’s disease, and thanks to its aphrodisiac effects, helps to improve sexual function and desire (much more so for men than woman) and I can atest to the fact that it does increase libido...wonderfully so
Conditions for which Deprenyl appears to be therapeutic or ameliorative include: cerebral infarction (stroke), hormone inadequacy, amyotrophic lateralizing sclerosis (lou gherig's disease), fatigue, chronic pain, gastric ulcers, senile dementia, sexual dysfunction, multiple sclerosis, learning difficulties, blepharospasm, hypertension depression and cancer.
Dr. Clyde Reynolds, a clinician who specializes in the metabolic therapy of cancer in Washington State, discovered that cancer patients invariably have imbalances of the neurotransmitters, epinephrine, norepinephrine and serotonin. Dr. Reynolds has found that Deprenyl is highly effective in restoring the normal levels and normal balance of these neurotransmitters. He believes that normalization of the balance of these neurotransmitters is an absolute necessity for the effective treatment of all cancers.
Dosage:
Parkinson and Alzheimer's disease patients are often treated with very high doses of 20mg daily (usually along with other drugs). Anti-aging doses (dependant on age and condition) are more likely to be 2.5mg to 5mg once, twice or three times a week, or, 1mg to 3mg per day, with regular breaks.
Deprenyl tablets are selegiline hydrochloride, which is deprenyl bonded to an in-organic molecule. However, liquid deprenyl citrate (LDC) is selegiline bonded to an organic molecule, one reason why the liquid deprenyl citrate is considered to be superior. This form is generally recognized as the most pure and potent form of deprenyl available. It also allows precise titration for anti-aging purposes, as each ml drop in the bottle is equivalent to 1mg deprenyl citrate - 1mg two times a week for 30 to 35 years olds up to 10mg daily for 80 year olds plus. Ward Dean, M.D., recommends reducing deprenyl doses after several months to lower levels and taking occasional sabbaticals.
After reading this...tell me you're not interested in trying it. I love the stuff and I told this to my Doctor directly and he just smiled and "yes, I do as well" with a wink.
This compound can be bought online without a script. Just Google either Seleginine or Deprenyl and you will find a number of outlets. Or, just ask your Doc (if you're Doc is in the know) to get it compounded for you. Not expensive and the upsides are simply fantastic.
Age. Dosage
30-35 1 mg twice a week
35-40 1 mg every other day
40-45 1 mg every day
45-50 2 mg every day
50-55 3 mg every day
55-60 4 mg every day
60-65 5 mg every day
65-70 6 mg every day
70-75 8 mg every day
75-80 9 mg every day
80 plus 10mg every day
Highly recommend my dear friends
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Originally Posted by kelkel
