Redz makes a good point.

Time and time again I have seen meds behave differently in cancer patients than healthy subjects, but that doesn't mean the data can be put aside.

Estrogen plays a vital role in bone mineral density. SERMs, which expression the ER in bone (Tamox, Clomid, Tore) because they're agonists in this tissue, positively effect bone mineral density, so when estrogen is lowered it can cause negative side effects, such as the above.

We have to remember how often we use AI's and HOW MUCH we lower estrogen. Put simply, we dont want a "65%" reduction, we want to put it in normal ranges with the correct dose. That said, I can't see how Aromasin, or any other AI can cause problems in bone mineral density if estrogen is kept in normal ranges. Lowered ranges, yes. Crushed completely, then you cause more problems.

Do you have the full paper of this study?