exemestane, having issues...

[decaDump]

Ok guys im currently on cycle..

500mg test e e3d
200mg nandrolone dec e3d
50mg winstrol ed
100mg oxandrolone ed

heres the problem...

I started out with 20mg exemestane ed, got e2 sides... increased to 40mg. Feeling better but still e2 sides. I have found myself taking 40mg in the morning and then another 10-20mg later throughout the day as it feels like e2 sides come on. Now i cant find a definitive source for half life. Some states 12-27hrs.

Now i must admit i seem to hyperaromatase androgens. On trt dosages i needed adex and was almost at .5mg a day.

Not many people i know use exemestane so looking for feedback on others that have used it.

Im going to continue with 60mg a day. Its just some people state 12mg is needed e2d so its doing my head in.

Dude, you're taking too much at once. KISS method, my friend.

"It's not what you gain, it's what you maintain." dD

[The Bear 79]

"Exemestane reaches steady blood plasma levels of after a week of administration and this is also when we see it begin its maximal effect on reducing circulating estrogen levels. It’s also has a ½ life of 27 hours (4), so taking it once per day is going to build up blood plasma levels to a very effective level."

References:

1. A predictive model for exemestane pharmacokinetics/pharmacodynamics incorporating the effect of food and formulation.Br J Clin Pharmacol. 2005 Mar;59(3):355-64.

2. Eur. J. Cancer. 2000, May;36(8):976-82

3. The Journal of Clinical Endocrinology & Metabolism Vol. 88, No. 12 5951-5956Copyright © 2003 by The Endocrine Society

4. Clin Cancer Res. 2003 Jan;9(1 Pt 2):468S-72S

5. Anticancer Res. 2003 Jul-Aug;23(4):3485

6. J Clin Endocrinol Metab. 2003 Dec;88(12):5951-6.