Nolva vs. Nolva/Clomid

[Glassjaw]

I was going to start a thread about this myself.

Is clomid necessary? From my research I can't see why it is.

Most people would know that nolva and clomid are both SERM's, and I'm sure most have read that nolva is stronger. ie. 20mg nolva = 150mg clomid.

I've also read that nolva has no estrogenic effect on the pituitary, whereas clomid has a slight effect on it - not good on pct and probably also explains the mood effects it has on a lot of people.

So if both are SERM's, and achieve similar things. And we know from studies that 40mg of nolva is no more effective than 20mg. Why would 20mg of nolva AND 150mg clomid be necessary?? Especially if you consider the est effects on the pituitary.

I'm basing this on research I've done around the net, so I don't claim any of this to be fact. I would like to see a vet shed some light on the subject though.

[evander87]

I was going to start a thread about this myself.

Is clomid necessary? From my research I can't see why it is.

Most people would know that nolva and clomid are both SERM's, and I'm sure most have read that nolva is stronger. ie. 20mg nolva = 150mg clomid.

I've also read that nolva has no estrogenic effect on the pituitary, whereas clomid has a slight effect on it - not good on pct and probably also explains the mood effects it has on a lot of people.

So if both are SERM's, and achieve similar things. And we know from studies that 40mg of nolva is no more effective than 20mg. Why would 20mg of nolva AND 150mg clomid be necessary?? Especially if you consider the est effects on the pituitary.

I'm basing this on research I've done around the net, so I don't claim any of this to be fact. I would like to see a vet shed some light on the subject though.

I asked the question "why 2 SERMS?" a long time ago and while no studies were cited I was told that Nolva and clomid act on different receptors to block estrogen. Bro science or not I don't know.