My buddy get Tren cough almost immediately after he injects. I've only run fairly low dose of Tren (250mg/wk) and I didn't get any coughing fits. The Tren E should take about 4 weeks to kick in and the cough isn't as bad. When you mix the two esters you'll get a little bit of both sides. I'm assuming your Tren A dose is half and the Tren E dose is the other half.