The study listed in the OP comes from the American Journal of Physiology Endocrinology and Metabolism July, 2001.

A few points of interest:

*The study was for 20wks, meaning each man received his weekly dosing of testosterone each week for 20wks...this is important as a lot of people throw a hissy fit when a guy says he's going to run a cycle that's longer than a standard message board norm.

*No one in the study was given an Aromatase Inhibitor or any type of anti-estrogen, this includes the 600mg/wk group...this one is interesting on the basis that many tend to claim you have to use an AI to avoid gynecomastia. Tell that to the 13 men who ran 600mg/wk. Note: this isn't to say anti-estrogens are not valuable tools. Many, however, tend to rely on them far more than they should, especially when we consider the strong negative impact they can have on cholesterol.

*As the OP listed, all the men saw their HDL cholesterol decrease. However, it was only slightly. Even in the 600mg/wk group it was on by 9 points.

*The study concludes by stating we don't know the long term effects on the prostate. It's often been thought that high testosterone levels fed prostate cancer. In fact, for decades men with prostate cancer have had their serum testosterone levels purposely decreased. However, in recent years the opposite is being said by some. Abraham Morgentaler was one of the first (maybe the first) to bring forth the idea that men with low testosterone are at a far greater risk. His findings were brought to The Journal of the American Medical Association with an enormous amount of evidence to support his theory. The Korean Journal of Urology has also brought forth some sound evidence, as did the UK Androgen study.

Anyway, maybe no one finds any of this interesting but me. Just putting it out there.