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Thread: One month on TRT with no change?

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    Bloodwork in... not sure what it means.

    Hey guys. Today I got the results from the blood draw taken one week ago. Doctor's appointment on Monday. As for what it means... I am at a loss. I'll just post the numbers and text as they appear. Would love some input - there's a few outcomes I thought were possible, but this particular combination does not make sense to me.

    This draw was taken on a Friday morning a little after 8am. I do my shots on Monday mornings. I was not fasting. Lots of tests run here. It is quite thorough. Note that there are 2 different measurements for Estradiol. One is at the very top and one is at the very bottom of the list.

    ------

    ESTROGEN, SERUM FRACTIONATED
    Estradiol by tandem mass spectrometry. 45.8 Unit: pg/mL

    (NOTE)
    REFERENCE INTERVAL: Estradiol by TMS

    Access complete set of age- and/or gender-specific
    reference intervals for this test in the ARUP Laboratory Test Directory (aruplab.com).

    Estrone by tandem mass spectrometry. 46.9 Unit: pg/mL

    (NOTE)
    REFERENCE INTERVAL: Estrone by TMS

    Access complete set of age- and/or gender-specific
    reference intervals for this test in the ARUP Laboratory Test Directory (aruplab.com).

    Estrogens, Total. 92.7 Unit: pg/mL

    (NOTE)

    Reference interval of estrogens in serum in adults.

    Males 18 and older:
    Estrone - 9-36 pg/mL
    Estradiol - 10-42 pg/mL
    Total Estrogens - 19-69 pg/mL
    REFERENCE INTERVAL: Estrogens Total Calculation

    Access complete set of age- and/or gender-specific
    reference intervals for this test in the ARUP Laboratory Test Directory (aruplab.com).

    ----------------

    Free T4: 0.9 [0.71-1.85] ng/dL
    Free T3: 3.7 [2.4-4.2] pg/mL
    Prolactin: H 36.9 [3.5-19.4] ng/mL

    ------------

    Testosterone, Total Serum: 979 [280-1100] pg/mL
    SHBG: L 12 [13-71] nmol/L
    Testosterone, Free: H 306.8 [47-244] pg/mL
    Testosterone, % Free: H 3.1 [1.6-2.9]
    Testosterone, Bioavailable: H 800.5 [131-682]
    Albumin: 4.2 [3.3-4.8]

    ------------

    Thyroglobin Antibodies: 2.1 [0-14.4] IU/mL
    Thyroid Peroxidase @ <0.5 [0-3.9] IU/mL

    Insulin Like Growth Factor: H 544 [112 to 402] ng/mL

    (NOTE)

    Repeated and verified.

    ------

    ESTRADIOL, MALES, CHILDREN, POSTMENO
    Estradiol by tandem mass spectrometry 61.1

    Unit: pg/mL
    Duplicate request, charges credited.

    (NOTE)

    Reference interval of estradiol in serum in adults.

    Males 18 and older:
    Estradiol: 10-42
    REFERENCE INTERVAL: Estradiol by TMS.

    Access complete set of age- and/or gender-specific
    reference intervals for this test in the ARUP Laboratory Test Directory (aruplab.com).

    ---------------

    That's it.

    So a few things...

    1) For one, the shots are working. There's about 3 times as much testosterone in my body as there was before.
    2) SBGH is a little bit low. I don't know what that could mean or do.
    3) Insulin like growth factor is high. I don't know what is or what it means.

    4) Estradiol is high. No question. The question is, by how much? For some reason the test appears to have been done twice. I THINK they may have ordered the wrong test at first, and then did the right one afterward. Regardless, it is high.

    I'm not sure if it is inappropriately high or not, though, since right now my T is also above normal in most respects. Maybe the balance is right? Not sure how all that plays out.

    5) Prolactin is high, this time noticeably so. This one puzzles me. I know that lowering Prolactin can raise Testosterone, but I was not aware of anything that would drive it up by raising Testosterone. So once again, not sure what this could mean.

    6) Thyroid stuff is about how it was before. Free T4 near the bottom of the range, Free T3 near the top. Disappointed to see that Reverse T3 isn't on the results. For some reason I thought it would be.

    As far as how I feel, it's been pretty much the same as the previous posts. Not a lot to report. Sensitive/sore nipple issues have come and gone but never been more than a minor annoyance. For a while I was having extra hard/slightly painful erections and was a little bit concerned, but then they went away. Sometimes it's a been much easier to keep it up, but this has been on and off as well. A few times I've thought the clouds were parting just enough to start so see some of the missing feelings of excitement, libido, enjoyment of life, etc, but it has never passed much beyond a glimpse. These glimpses have been more common than they were off the therapy, but things are still not normal or right or good. It's a bit easier not to just lay around and mope, though. I've been a bit moody/emotional but there's a lot of confounding variables with changes at work, life, etc so it may not be related. I've gained a little weight, which may be muscle as my pants seem to fit about the same, or maybe not. Wife thinks I might have gained a little muscle (I don't work out).

    Overall, the changes have been pretty unimpressive and vague.

    So, that's it. I'd love any thoughts/input on what the tests might mean or how to proceed. Right now I'm pretty puzzled.
    Last edited by MrManGuy84; 09-14-2012 at 11:35 PM.

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