Originally posted by juiceon


Bah, Humbug!

While I agree that this information is great and helpful, it does not address our question Ss. As stated at the beginning of the explaination: "the goal is to be at highest blood concentrations for as many of the 10 weeks as possible." With that goal in mind, he proceeded with his calculations.

Our question, however, was whether it was beneficial to intentionally vary the blood concentrations (not drastically, but perhaps moderately or lightly) throughout the 10 weeks in an attempt to fool our receptors/feedback mechanism.

For example, I've been on cycles where, at week 7 of a 10 week cycle, I feel like I am not gaining enough. So, that week I added 500 mg of primo depot (in 2 shots, two days apart) and exploded out of the "slump" with a drastic increase in weight, size, and strength. Now, obviously over that 10 week cycle I did not achieve the highest concentration of primo depot over many or all weeks, but rather I had a spike of primo depot that proved to be very beneficial. So spikes are not always bad, and maintaining a constant blood level concentration is not always good (but I will agree that it is good to a point).

I believe that a perfectly constant blood level concentration leads to faster receptor downgrade. I further believe that your body responds positively to spikes, albiet for a short period of time, but that has proved in my case to be enough time to catapult me through the final weeks of a cycle. These spikes exist on top of, basically, a constant blood level concentration.

This all has a lot to do with physiology, and muscle growth cycles from stimulation, to breakdown, to recovery, to growth. It is very complicated and involves many factors. Why is it that one will not grow at a constant rate for the entire duration of a cycle of 30 weeks of 500 mg. enanthate? How do our bodies respond to "fight" the administration of test (beyond the conversion to estrogen)? The answers to these questions, in conjunction with the explaination given at the beginning of this thread, will provide a more complete picture of this whole topic. I don't have the answers, only questions . . .
If you look at all the research with medicinal androgens where body weight gain is considered, you will see that there is an increase in body mass that occurs usually within the first six to eight weeks of treatment but does not increase after that (at the same dose) regardless of the duration of treatment. What this means is that you can grow so much off of a dose and then you will not grow anymore unless the dose in increased. I don't think this apply's to all BBers since most guys use doses so high that would provide similar gains in body mass if the same cycle is repeated over and over again.

The point is, increase the dose, increase the gains. You said you were stuck on a plateau and then you increased your dose and you grew some more. Does that surprise you? Do you think it has more to do with the over-all dose increase or, as you say, "spiking" androgens?

The best gains from AAS come from the most stable blood concentrations. Look at dbol. It is TREMENDOUSLY more effective if taken all throughout the day rather than once or twice a day. Same with injectable AAS-- You will grow more with a weekly dose of enanthate over a weekly dose of propionate-- Why? More stable blood concentrations.

Lastly, I have to disagree with "spiking blood concentrations= less receptor down regulation." Can you point me to a reference for this?

Andy