E2 raising with 250iu x2 a week of HCG. lower dosage?

[jaxbrah]

Im feeling the symptoms of elevated e2 levels. Nipple itchiness, breast tenderness, swelling, bloatedness ect. From what I read hcg can really spike your e2. Should I lower my dosage to about 100ius 2x a week?

My doc is waiting for my bw so I figured id get opinions from here in the meantime. Hes against the use of arimidex, and quite frankly so am I. So, I was curious if this could be an effective method as well.

Also, the goal is to keep the boys in good shape as well, so I hope 100 x2 a week is enough

[EverettCD]

Instead of 250iu 2X's per week, I would do 100iu 1X's per day Monday thru Friday. Much less chance it will spike your E2 on that dosing schedule.

[jaxbrah]

Instead of 250iu 2X's per week, I would do 100iu 1X's per day Monday thru Friday. Much less chance it will spike your E2 on that dosing schedule.

Interesting. So even though the amount is the same, it will affect my e2 levels less due to the lower amount per dose?

[Nofate]

I am experiencing an estrogen spike at the same 250iu x2 dosage too. Within hours of taking it, I also get the mental aspects - just become bitchy and irritable, negative, libido and appetite disappear. Within about 24 hours most of it is back to normal.

It has to be working though as my testicles have never been bigger and ejaculate volume is up.

I am thinking about going ED with a micro dosage of 50iu a day and see how that works.

JaxBrah - What Brand of HCG are you using?

[Rida5d]

Well.. I'd modify my AI intake if I were you.
I've never heard of going low to 100 iu twice..
How did u know it was hcg? Why ur doc is against an AI ? And are u on cycle?

[jaxbrah]

I am experiencing an estrogen spike at the same 250iu x2 dosage too. Within hours of taking it, I also get the mental aspects - just become bitchy and irritable, negative, libido and appetite disappear. Within about 24 hours most of it is back to normal.

It has to be working though as my testicles have never been bigger and ejaculate volume is up.

I am thinking about going ED with a micro dosage of 50iu a day and see how that works.

JaxBrah - What Brand of HCG are you using?

im using pregnyl. It seems my ejaculate amount is actually lower than before but more "testing" is required. I was feeling great after my first week of trt, sex drive, energy, confidence. But after week 2 I noticed the e2 symptoms and loss of libido, energy. I will say though that ive been feeling a little better the past couple days.

[jaxbrah]

Well.. I'd modify my AI intake if I were you.
I've never heard of going low to 100 iu twice..
How did u know it was hcg? Why ur doc is against an AI ? And are u on cycle?

Not on cycle, 100mg t cyp per week. Hes against ai because long term ai use can be damaging to you since low e is bad for you as well. The last time I took arimidex I took a lose dose of .25 of a pill and my e2 levels were still below acceptable range. Id rather not even mess with it if I dont need it

[kelkel]

Use DIM and Zinc if you only have minor E2 issues. And Everette is correct. Consider splitting your Test into two injections per week as well to mitigate E sides.

[jomamma007]

I had the same issue, on the days I would take hcg I would get mad anxiety but it would only last the day.
Split injections into two 50mg shots, ideally 3.5 days apart
add in 200mg DIM, 50mg zinc, and 2-3mg copper if your e is only slightly elevated.

Not quite sure but it sounded like you had high e2 symptoms even before adding hcg as you said you felt them in week 2. If that's the case the hcg will definitely exacerbate the situation.
We need blood work though. You might be able to get away with simply splitting your dosage in half and injecting twice per week. Also depending on your labs, you might be able to lower the dosage, as it is pretty commonly accepted that the ideal hrt is test+hcg without an ai.

Personally I just stopped taking hcg last week and feel better without the mood swings, but ideally you'd want to include it for the benefits it produces.

[jaxbrah]

I had the same issue, on the days I would take hcg I would get mad anxiety but it would only last the day.
Split injections into two 50mg shots, ideally 3.5 days apart
add in 200mg DIM, 50mg zinc, and 2-3mg copper if your e is only slightly elevated.

Not quite sure but it sounded like you had high e2 symptoms even before adding hcg as you said you felt them in week 2. If that's the case the hcg will definitely exacerbate the situation.
We need blood work though. You might be able to get away with simply splitting your dosage in half and injecting twice per week. Also depending on your labs, you might be able to lower the dosage, as it is pretty commonly accepted that the ideal hrt is test+hcg without an ai.

Personally I just stopped taking hcg last week and feel better without the mood swings, but ideally you'd want to include it for the benefits it produces.

I started the hcg at the same time I started t. I had a sex drive for the first time in my life pretty much for that short period of time. Im 27 and have a prolactinoma which is causing secondary hypogonadism. Pretty sure ive had the issue since I was 13.

anyway, yea I think ill go with hcg ed 100iu and t cyp at 50mg on weds and saturday. I also take cabergoline for the prolactinoma.

Im thinking maybe I went through a spiking period and now im leveling off some as my body adjust to these exoveneous hormones.

2 years ago I did trt with adex, hcg 250 3x a week and my initial bw had my T levels at 1800 day after injection and e2 levels in single digits. Im assuming I am hypersenisitve so something, maybe arimidex or hcg. Considering im secondary, mayne its the hcg since my boys are ok to begin with

[EverettCD]

Interesting. So even though the amount is the same, it will affect my e2 levels less due to the lower amount per dose?

Yes. As many do with Testosterone injections, lower more frequent dose will lessen the E2 spike. I do the same with my HCG, my Dr originally Rx my HCG at 500iu every 3.5 days for convenience. I asked him about injecting it more often & he said that's good as well, as long as I'm getting 1000iu per week I'm good to go. I inject 150iu per day & that works well for me.

[Charlie6]

What is DIM?

[LowT Mike]

Di-Indole Methane. Works great. 120-200mg per day along with Zinc-50-75mg/copper 2-3mg help greatly with theP-450 liver enzyme in metabolizing free circulating estrogen in the body. Where as Arimidex/Anastrozole blocks testosterone production.

Jaxbrah-- Im sorry but Im really hard pressed to be convinced your E2 is elevated due to the 250IU of HCG 2x per week. Ive treated thousands of men and never seen excited E2 at that dose. I would be more inclined to say it was your Testosterone converting to E2 and you just need anastrozole or DIM/ZINC/COPPER combo. or split your doses throughout the week. Find works best for you by stagging with regular blood work. Not that hard to get a nice tailored fit with the right physician. Nothing at all wrong with anastrozole as long as you keep your E2 levels between 20-30pg/ml. Just dont want to crash them to 0. Your brain and heart need some E2 to protect surrounding vessels.

[powerlifterty16]

Di-Indole Methane. Works great. 120-200mg per day along with Zinc-50-75mg/copper 2-3mg help greatly with theP-450 liver enzyme in metabolizing free circulating estrogen in the body. Where as Arimidex/Anastrozole blocks testosterone production.

Jaxbrah-- Im sorry but Im really hard pressed to be convinced your E2 is elevated due to the 250IU of HCG 2x per week. Ive treated thousands of men and never seen excited E2 at that dose. I would be more inclined to say it was your Testosterone converting to E2 and you just need anastrozole or DIM/ZINC/COPPER combo. or split your doses throughout the week. Find works best for you by stagging with regular blood work. Not that hard to get a nice tailored fit with the right physician. Nothing at all wrong with anastrozole as long as you keep your E2 levels between 20-30pg/ml. Just dont want to crash them to 0. Your brain and heart need some E2 to protect surrounding vessels.

mike isnt it always testosterone converting to e2? men don't have any other way to make estrogen? lol
I had no idea adex inhibits t production! One more reason to try to dial yourself in to the point that you can go without adex.

[Low Testosterone]

Just because you're taking testosterone or other compounds that increase testosterone does not mean it's converting to estrogen and estradiol levels are going up. I would say 25-30% of our clients are prescribed no AI. Why? Their estradiol levels are not elevated. Myself, I've been on TRT for close to 4yrs and I've never taken an AI. My estradiol stays in the high teens to low 20's regardless of my testosterone dose or HCG dose.

[dreadnok89]

[QThat's why LowT Mike;6697219]Di-Indole Methane. Works great. 120-200mg per day along with Zinc-50-75mg/copper 2-3mg help greatly with theP-450 liver enzyme in metabolizing free circulating estrogen in the body. Where as Arimidex/Anastrozole blocks testosterone production.

Jaxbrah-- Im sorry but Im really hard pressed to be convinced your E2 is elevated due to the 250IU of HCG 2x per week. Ive treated thousands of men and never seen excited E2 at that dose. I would be more inclined to say it was your Testosterone converting to E2 and you just need anastrozole or DIM/ZINC/COPPER combo. or split your doses throughout the week. Find works best for you by stagging with regular blood work. Not that hard to get a nice tailored fit with the right physician. Nothing at all wrong with anastrozole as long as you keep your E2 levels between 20-30pg/ml. Just dont want to crash them to 0. Your brain and heart need some E2 to protect surrounding vessels.[/QUOTE]


That's why I use exestamane, it never kills all your estrogen. Its gets your free-t pretty good too


Thats

[jaxbrah]

Di-Indole Methane. Works great. 120-200mg per day along with Zinc-50-75mg/copper 2-3mg help greatly with theP-450 liver enzyme in metabolizing free circulating estrogen in the body. Where as Arimidex/Anastrozole blocks testosterone production.

Jaxbrah-- Im sorry but Im really hard pressed to be convinced your E2 is elevated due to the 250IU of HCG 2x per week. Ive treated thousands of men and never seen excited E2 at that dose. I would be more inclined to say it was your Testosterone converting to E2 and you just need anastrozole or DIM/ZINC/COPPER combo. or split your doses throughout the week. Find works best for you by stagging with regular blood work. Not that hard to get a nice tailored fit with the right physician. Nothing at all wrong with anastrozole as long as you keep your E2 levels between 20-30pg/ml. Just dont want to crash them to 0. Your brain and heart need some E2 to protect surrounding vessels.

If my T is converting to e2 then my e2 levels are still raised...so im not quite sure what you were trying to say there. I will definitely be trying the DIM / zinc combo however.

what kind of t levels do you get with 50mg 2x a week compared to 100mg per week? Wouldnt the 50mg be lower but more consistent?

[LowT Mike]

You are saying in your first thread that your E2 is elevated due to HCG and you started titrating HCG dose down from an already low dose HCG. Not the avenue I would look at. most E2 conversion is from Test aromatase. Thats my point. But everyone is different. Its not one size fits all. But on the other hand its not that hard to get your E2 in check with a good AI or Zinc/copper/DIM combo. E2 conversion also depends on body fat %.

[powerlifterty16]

Not on cycle, 100mg t cyp per week. Hes against ai because long term ai use can be damaging to you since low e is bad for you as well. The last time I took arimidex I took a lose dose of .25 of a pill and my e2 levels were still below acceptable range. Id rather not even mess with it if I dont need it

are you sure your gear isn't bunk? they don't make pregnyl anymore.