Big results with Pregenelone!

[hammerheart]

That doesn't surprise me, pregnenolone converts to progesterone, and in the brain conversion to allopregnenolone happens. It's a powerful allosteric agonist at the GABA-A receptor and works much like the benzos.
Paradox reactions might also occur. 50mg oral pregnenolone is what I consider an hefty dosage and overdose is likely to occur in predisposed individuals.

[jstone]

That doesn't surprise me, pregnenolone converts to progesterone, and in the brain conversion to allopregnenolone happens. It's a powerful allosteric agonist at the GABA-A receptor and works much like the benzos.
Paradox reactions might also occur. 50mg oral pregnenolone is what I consider an hefty dosage and overdose is likely to occur in predisposed individuals.

Thanks. The wierd thing is I used to use 100mg daily, and had none of the sides. Maybe this is higher quality. I knew it could up e2, and prolactin it just didn't happen before. I will try taking 25mg eod to start again.