Quote Originally Posted by GearHeaded View Post
great subject .. I'll add just a couple simple points at a time (try to limit my long winded wordy posts that make guys eyes glaze over).

to go direct to the point with an answer (which I've actually touched on in several other posts lately regarding the 3HSD enzyme and DHT)

things like VAR and Winny are DHTs .. SO.... since they already 5-alpha reduced, they cannot be reduced further by 5-alpha reductase enzyme (which is what a DHT blocker does, ie., block 5 alpha). Due to the presence of the oxygen atom in the A-ring, this steroid is not deactivated by 3-alpha hydroxysteroid dehydrogenase (3HSD) in skeletal muscle. . 3HSD is an enzyme that is found in skeletal muscle that deactivates circulating DHT, rendering it inactive.

I talk about this in my Estrogen is more anabolic then DHT thread.. stating that Estrogen is not effected by this enzyme and is therefore more anabolic in muscle tissue then DHT is


hope that makes sense.
Yez that post is what mafe me ask the question.
Your posts are well recieved, never too long brother and I appreciate it.

What would you recommend for a daily dosage in your opinion to prevent hair loss in someone on a heavy ass cycle?