there is no doubt that oral AAS use will negatively effect cholesterol profile, especially lower HDL (the so called good cholesterol) . HOWEVER , just because this is how the blood work shows up while on these orals, does not necessarily mean thats a bad thing or going to cause any health problems. its just a number on a piece of paper... heck there may be reasons that oral AAS lower HDL that we are actually getting a benefit from (or that the body lowers HDL while on these compounds because we simply require less of it).
Until we have real evidence that AAS lowering HDL is actually a proven "bad thing", I don't think we can say for sure. there are other factors to consider like if HDL comes back to range when off of AAS , or testing cholesterol particle size.
I would say though , that IF cholesterol is a major health priority for you and managing good HDL levels is important . then I would NOT run Arimidex for your cycles at high dosages for that long . Your cholesterol will be much better off running a SERM for estrogen control , as a SERM is only blocking E at the receptor sites like breast and fat tissue, but allowing the good receptor sites in the liver to still function and produce HDL (whereas an AI does not do this . . its lowering total estrogen levels and thus limiting e from passing through the liver for HDL production).





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