This. Many people do not realize they have GI issues until they hit Tren. From a detailed discussion with a GI specialist use of OTC antiinflamatories or Advil/tylenol at a regular interval results in GI Tract irritation over 90 percent of the time. I think most people who cycle use these so it should be expected. From my experiences doses over 75 mg a week cause these sides while 75 and under a week do not. The acid reflux also appears to not be impacted by prilosec.