If you can add at least 1mg of MSM to the mix, it will have an even greater effect. Many companies are making the 3 component combos now, but MSM really does add to the benefits of gluc/chond. I take 3mg/2.5mg/2mg(gluc/chond/MSM) daily and am loving the effects. There are also said to be fat-burning properties at these doses and higher, but there is no good explanation as to the mechanism, so I'm not sold on that. As for my joints, they're loving it. The cost/benefit to this supp is invaluable.Originally Posted by Iron006