I guess I've been lucky as to have never experienced anything like that.Originally Posted by Red Ketchup
I guess I've been lucky as to have never experienced anything like that.Originally Posted by Red Ketchup
ECA stack works fine for me with out the a...i heard that asprin thins your blood wich allows more blood to be pumped?? is that makes any sense![]()
please see my previous post:
http://anabolicreview.com/vbulletin/...ad.php?t=80190
and i'll kindly ignore daman1 posting that without quoting me... jk man.. i don't mind as long as its in the right context... which it was.
as in the dose of ASA required, 81 mg might be too little. Doses as low as 50mg have been shown to have antiplatelet effect. But to illicit the anti-inflammatory effect of ASA, you need doses closer to 325mg. Why is this important? ASA's inhibition of prostaglandin production is what gives it its antiinflammatory property. Also, ASA is used in flushing caused by Niacin. The vasodilatory effect of niacin seems to be caused by prostaglandins. The 325mg dose has been shown to be better at reducing the flushing effect than an 81mg dose. From this you may be able to postulate that the 325mg dose is better at inhibiting prostaglandin production than and 80mg dose.
ASA increases the risk of duodenal and gastric ulcers and lower GI bleed as well. The use of an enteric coated ASA has been shown to decrease the risk of this. There have also been issues with caffeine causing GI hemorrhage and gastritis but this has only been really shown in newborns being given caffeine for apnea. Most of the data involving caffeine causing GI disturbances in adults is comprised of case reports.
I answer the "more blood to be pumped" issue in the link provided.
Theoretically, it is a positive to take the aspirin in the ECA stack but I don't think its ever been studied whether the risk outweighs the benefit. I'll do a lit search when i get a chance to see if anyone has ever looked into that. Also, I'm interested in seeing what the longest is that an ECA stack has been studied and to see if they've reported any increased side effects with increased dose or duration of therapy. I'll keep you posted on anything that I may find.
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