Quote Originally Posted by einstein1905
No, cholesterol-based hormones are not big enough to illicit an immune response. Even with a long ester attached, it's not happening. Sticking a needle into your flesh and injecting something containing some alcohol will cause localized tissue damage. The slight tissue damage results in inflammatory factors being recruited to the site, but this is in no way specific to the hormone.
HUH? you can definitely have an allergic reaction to steroids. there are a few threads that describe a body rash after injecting steroids. that sounds like a drug allergy to me.