Aspirating... why?

[Lemonada8]

You will not die if you hit a vein with a shot unless you shoot over a CC of air with it.

You shoot IM so that there is a slow and steady release of a drug. The muscle acts as a depot for the drug to prolong its release and to keep the drug at a constant level in the blood. If you hit a vein all that drug goes into the circulation and has a high serum concentration for a short period of time relative to an IM depot. With some drugs a huge spike into the blood can be dangerous. These are usually drugs that alter metabolism rapidly.

Lastly if you hit a vein as apposed to an artery. The venous pressure is only about 20 % of what it was after it left the heart by the time it gets back to the heart. If your in a vein it really depends on were it is at and like Lemonade8 said if the muscle is contracted to whether it will shoot into the needle without aspirating.

Really there is no reason not to aspirate, and chances are if your in a vein anyway and do not aspirate you will still bruise.

so... hypothetical ? for ya... if u shoot test IV, would that increase your metabolism? (along w/ super bad sides and such)

[playboii]

I agree, but we all have to respond like he is so that some newb doesnt stumble onto this bear trap of a thread and start injecting himself improperly.

very true

[MuscleScience]

so... hypothetical ? for ya... if u shoot test IV, would that increase your metabolism? (along w/ super bad sides and such)

Not instantly, if you remember from your physiology class, steroid hormones of all kinds are slow to cause change and long acting. As opposed to second messenger hormones such as epinephrine that activate the IP3 signaling pathways in alpha receptors and AC signaling pathways in beta receptors.

The reason steroids are slow acting is because they have to:
1. unbind from there transport proteins (because they are hydrophobic)
2. diffuse across the cell membrane
3. bind with a Hormone Response Element (HRE) or better known as a
nuclear steroid receptors.
4. cause transcription of mRNA's
5. translation of proteins from mRNA via the ribosomes
6. modification of proteins by the rough ER and the Golgi.
7. Protein transport and or signaling to create new proteins ect.

Were as the second messenger hormones already have all the responding elements in place at the time of hormone presentations to its membrane receptor.

I know you know this Lemonade8 I am just pointing it out to those who havent had cell bio like us and really wanted to know......

[stpete]

OK, i just put a 25 gauge in a vein in my arm for 3 minutes. No blood at all.
I was tempted to put a little tren in there to see what would happen but decided against it.

[playboii]

OK, i just put a 25 gauge in a vein in my arm for 3 minutes. No blood at all.
I was tempted to put a little tren in there to see what would happen but decided against it.

[JiGGaMaN]

lol@ why aspirate?...he can't be serious

Why cant I be? I think it would be much more enriching a discussion than the typical 'this is my first cycle, why am i a moron?' thread. Day 25 into no aspirating ed injections... still here.

[playboii]

Why cant I be? I think it would be much more enriching a discussion than the typical 'this is my first cycle, why am i a moron?' thread. Day 25 into no aspirating ed injections... still here.

well you can call yourself lucky...you hit a vain, inject AAS in there..not good...if you search around here you'll find threads about people that had injected aas without aspirating and you'll see why you always should.

[JiGGaMaN]

well you can call yourself lucky...you hit a vain, inject AAS in there..not good...if you search around here you'll find threads about people that had injected aas without aspirating and you'll see why you always should.

If they injected with out aspirating and supposedly hit a vein, theres no way of knowing for sure because they didnt aspirate to confirm anyhow. Either way im having a hard time finding any such posts where this occurs.

[playboii]

If they injected with out aspirating and supposedly hit a vein, theres no way of knowing for sure because they didnt aspirate to confirm anyhow. Either way im having a hard time finding any such posts where this occurs.

alright then suite yourself

[stpete]

If they injected with out aspirating and supposedly hit a vein, theres no way of knowing for sure because they didnt aspirate to confirm anyhow. Either way im having a hard time finding any such posts where this occurs.

Let's just shoot shit in our bodies with no regard whether it might go directly to our heart. This is living on the edge and i'm down!! Why don't we just inject in our veins? Oh, that's right, it might kill us. This takes all the fun out of it!

[JiGGaMaN]

Let's just shoot shit in our bodies with no regard whether it might go directly to our heart. This is living on the edge and i'm down!! Why don't we just inject in our veins? Oh, that's right, it might kill us. This takes all the fun out of it!

Thats blowing things just a bit out of proportion. I would suspect shooting test directly into a vein would not kill you anyhow.

[stpete]

Thats blowing things just a bit out of proportion. I would suspect shooting test directly into a vein would not kill you anyhow.

I wouldn't try it bigman!! haha......I'm not blowing anything out of proportion my man. Juice needs to be shot in the muscle! There's no way that i would go through all the training and dieting just to put a needle in myself and not be 100% sure that it's going to the right place.
Just me though. To each their own. But i will tell you this: i hit a vein once, and when i withdrew, blood shot 6 feet and it scared the shit out of me. This was in 1997 and i didn't aspirate. I think i went through the vein actually.
Anyway, my buddies(paramedics) showed me the correct way of injecting. I haven't had a problem sinse.

[JiGGaMaN]

I wouldn't try it bigman!! haha......I'm not blowing anything out of proportion my man. Juice needs to be shot in the muscle! There's no way that i would go through all the training and dieting just to put a needle in myself and not be 100% sure that it's going to the right place.
Just me though. To each their own. But i will tell you this: i hit a vein once, and when i withdrew, blood shot 6 feet and it scared the shit out of me. This was in 1997 and i didn't aspirate. I think i went through the vein actually.
Anyway, my buddies(paramedics) showed me the correct way of injecting. I haven't had a problem sinse.

Didnt happen to be in the delt did it? For some reason the blood spray only seems to happen there (its happened to me as well).

[widescreen]

When I aspirate, it's hard to pull the plunger back - I never get any blood. When I pull the needle out of my glutes after, I usually get some blood coming out of the injection site. Does the blood mean I'm hitting a vein? I'm never in any pain.

[JiGGaMaN]

When I aspirate, it's hard to pull the plunger back - I never get any blood. When I pull the needle out of my glutes after, I usually get some blood coming out of the injection site. Does the blood mean I'm hitting a vein? I'm never in any pain.

at one point you ruptured or passed through a vein. that is all.

[widescreen]

Thanks Jiggaman; am I doing something wrong? Should I move over a bit, from my typical inject location? I'm with you on the why bother aspirating argument - I'm pretty sure if you start injecting in a vein, you'd know cause of the pain. We're supposed to be injecting slow, so shouldn't you be able to catch yourself in the act, if you were? I'm probably way off, so tell me if I'm wrong.

[stpete]

Didnt happen to be in the delt did it? For some reason the blood spray only seems to happen there (its happened to me as well).

No, actually it sprayed from my right glute. I painted my wall with blood. hahahaha
My stuff comes from people in the medical field, and they showed me a long time ago how to do things(after this incident).

I'm just thinking: What would happen if some juice was in your veins?

[spiromik]

dont worry about aspirating.. just inject into the blood stream.. u feel like ur gonna die for abit but u will b fine later... hehe joke

[Batlin MD]

So guys... if you get blood in the syringe, do you pull out the needle and move on a few cm then go in again and re-asperate? Do you change your needle for a new one before? Just curious.

Bat

[JiGGaMaN]

In that situation i wouldnt take it completely out and start over, just move a bit to the left or right.