
Originally Posted by
2Sox
I would advise you be very careful with this dosing schedule. I'm learning that although exemestane is a much "gentler" AI than adex, it still does its job VERY well, and I am seeing - from what I'm experiencing now - that low E2 can literally sneak up on you - especially with exemestane which doesn't have that rebound effect.
I was dosing 6.25mg/day for awhile and my libido and night/morning erections gradually started to disappear. "Gradually" is the key word here. I've been thinking hard on this (no pun intended) for some time now. This is how I see it: Any AI can be used more frequently at the beginning of treatment ONLY - to get E2 levels down to an ideal level. But then you have to find the dose that works long term - to keep that ideal level stable. THAT'S the trick, as I see it.
Edit: As a general rule, I think the best approach would be to just to start out low until you see results. I don't see the necessity of hitting E2 hard unless there is an urgent issue, like gyno.
I know my E2 is low now; low energy, low libido, poor erection quality. Nothing horrible but just no fun, no spark. So I'm cutting back to 6.25mg every 4 days. I'll report back to you all. But I'd really like to know other's thoughts on this.