
Originally Posted by
AlphaLdr
Wikipedia say
Adverse effects
Most adverse effects resemble vitamin A toxicity. Adverse drug reactions associated with isotretinoin therapy include:[1]
Common: mild acne flare, dryness of skin, lips and mucous membranes, cheilitis, itch, skin fragility, skin peeling, rash, flushing, photosensitivity, nose bleeds, dry eyes, eye irritation, conjunctivitis, reduced tolerance to contact lenses, hyperlipidaemia, raised liver enzymes, headaches, hair thinning, myalgia and/or arthralgia.
Infrequent: severe acne flare, raised blood glucose level, increased erythrocyte sedimentation rate, fatigue and/or mood changes.
Rare: impaired night vision, cataracts, optic neuritis, menstrual disturbances, inflammatory bowel disease, pancreatitis, hepatitis, corneal opacities, papilloedema, idiopathic intracranial hypertension, skeletal hyperostosis and extraosseous calcification.