Niacin

[Quester]

I've got a blood test/physical coming up in a few months so I've been researching. I want to take Niacin for cholesterol but just found out, at doses high enough for positive effect on cholesterol, niacin is associated with impaired liver function. This applies to immediate release (IR) and slow/Long acting (extended release ER). The only one acceptable is the prescription one, go figure, Niaspan, it has a different formulation.
Here's the article:
//www.mdedge.com/jfponline/article/60319/hepatology/should-liver-enzymes-be-checked-patient-taking-niacin

[GearHeaded]

yep I've heard this before.. thats why I have a giant bottle of Niacin thats been sitting in my cabinet for two years not being used.

[kelkel]

So start with a lower amount of Slo-Niacin or Endur-Acin and check bloods in a few months. I've been running one or the other for probably 5 years now with zero issues and I do blood work constantly.

[GearHeaded]

I've ran so many orals, and still enjoy taking them especially pre workout. plus I enjoy my whisky on occasions. so was always afraid of any supplement that might further raise liver enzymes without having enough a plus side (you know like Dbol and whisky have

[Quester]

The article did state that docs run LFTs on their patients, Niaspan ones, regularly. Perhaps for those of us on TRT (regular blood tests) a Niacin formulation isn't a problem.
I've read that the UK has drugs used for Non-Alcohol Fatty Liver, might also be worth looking into. Maybe they got something for both?

[Quester]

GH,
That's exactly my concern.

[MuscleScience]

Awesome guys, thanks for sharing. I have literal never heard that before, good to know.

[almostgone]

So start with a lower amount of Slo-Niacin or Endur-Acin and check bloods in a few months. I've been running one or the other for probably 5 years now with zero issues and I do blood work constantly.

Same here for the last 2 years or so. Running Slo-Niacin and my lipids and liver enzymes are generally pretty darn good and not on any script statins or anything. Figure it couldn't hurt given the clotting disorder.
Just looking at my last post blast labs:

Total cholesterol - 134 range is 100-199mg/dL
Triglycerides -54. range is 0-149 mg/dL
HDL 44 range is greater than 39 mg/dL. I'm an old fart on TRT so throw a few more points to that value.
VLDL 11 range is 5-40
LDL 79 range is 0-99
ALP 57 range is 39-117
AST 26 range is 0-40
ALT 30 range is 0-44
Total globulin 2.3 range 1.5-4-5

[MuscleScience]

Same here for the last 2 years or so. Running Slo-Niacin and my lipids and liver enzymes are generally pretty darn good and not on any script statins or anything. Figure it couldn't hurt given the clotting disorder.
Just looking at my last post blast labs:

Total cholesterol - 134 range is 100-199mg/dL
Triglycerides -54. range is 0-149 mg/dL
HDL 44 range is greater than 39 mg/dL. I'm an old fart on TRT so throw a few more points to that value.
VLDL 11 range is 5-40
LDL 79 range is 0-99
ALP 57 range is 39-117
AST 26 range is 0-40
ALT 30 range is 0-44
Total globulin 2.3 range 1.5-4-5

Those do look pretty darn descent. I’ve never in my life had HDL’s over 45 even in my early 20’s.

[Mr.BB]

I've got a blood test/physical coming up in a few months so I've been researching. I want to take Niacin for cholesterol but just found out, at doses high enough for positive effect on cholesterol, niacin is associated with impaired liver function. This applies to immediate release (IR) and slow/Long acting (extended release ER). The only one acceptable is the prescription one, go figure, Niaspan, it has a different formulation.
Here's the article:
//www.mdedge.com/jfponline/article/60319/hepatology/should-liver-enzymes-be-checked-patient-taking-niacin

Try amla powder also: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326920/

Im sure it will be cheaper. Put the powder in capsules as it tastes really bad. It increased my HDL to 65, and lowered my LDL 10-15mg.

[kelkel]

Try amla powder also: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326920/

Im sure it will be cheaper. Put the powder in capsules as it tastes really bad. It increased my HDL to 65, and lowered my LDL 10-15mg.

BB from what to 65? Do you recall?

[Mr.BB]

BB from what to 65? Do you recall?

low 40's... Max i remember was 48.

[kelkel]

low 40's... Max i remember was 48.

Impressive. Eventually I'm going to have to try that.

[Mr.BB]

Impressive. Eventually I'm going to have to try that.

Its cheap stuff

[Oliver47]

I've taken Niacin off and on for years. As mentioned above, they keys are:

1- building up the dosage slowly.

2- taking with food in your stomach

3- never take when you are somewhat dehydrated or have alcohol in your system.

The stuff is cheap and does great things for your cholesterol. I usually take just before bedtime. More on https://www.fvkasa.org/english/healt...ills-drug-test

[Cornish]

I took increasing dosages of Niacin, drank copious amounts of water and sweat in a sauna for 5 hrs/day for 63 conswcutive days. Pretty sure I hit the 5 g mark. Felt like a new person afterward.

Sent from my SAMSUNG-SM-J327A using Tapatalk

[Oliver47]

Niacin is definitely worthwhile trying, so do ask your doc. If you've optimized your diet and you're exercising and the HDL is still low and the LDL is high, you could see significant benefit. Niacin can also lower triglycerides (read more on it on Canada Drugs). Unless something new comes along, yes, it might be long term use. You could try it for a while and recheck the lipid panel. Keep in mind that many people do well on statins, so you could fall back on that option if the niacin doesn't do the trick.

[beanpo1e]

With 250mg doses im on fire and my skin is burning. How do you tolerate 4-5g per day? I have heard Aspirin helps.

[xxblazenlowxx]

With 250mg doses im on fire and my skin is burning. How do you tolerate 4-5g per day? I have heard Aspirin helps.

I take it rite before bed