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  1. #1
    CRUISECONTROL's Avatar
    CRUISECONTROL is offline Post Whore Extraordinaire Cruising On Autopilot
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    Question about prescribed drugs affecting cylcle results

    Do drugs such as anti inflamatory, muscle relaxers and other pain relievers while taken during cycle lessen cycle results????

  2. #2
    Dizz28's Avatar
    Dizz28 is offline I reject your reality and substitute my own
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    "Neither drug had any influence on whole body protein breakdown, as
    measured by rate of phenylalanine appearance, on serum
    creatine kinase, or on rating of perceived muscle soreness
    compared with PLA. These results suggest that over-thecounter
    doses
    of both ibuprofen and acetaminophen suppress
    the protein synthesis
    response in skeletal muscle after eccentric
    resistance exercise

    Ibuprofen and acetaminophen are purported to relieve
    muscle soreness and pain through separate mechanisms.
    Ibuprofen is known to block cyclooxgenase (EC
    1.14.99.1), which then reduces metabolites produced by
    this enzyme, such as prostaglandins, that are at least
    partially responsible for inflammation and algesia (14,
    35, 36). However, prostaglandins have also been shown
    to regulate protein metabolism, and NSAIDs similar to
    ibuprofen have been shown to blunt protein metabolism
    in animal skeletal muscle (24, 30). Therefore,
    skeletal muscle protein metabolism may be influenced
    in individuals who consume ibuprofen after unaccustomed
    exercise. The mechanism of analgesic action of
    acetaminophen, also known as paracetamol, is less
    clear; however, it is believed to have its analgesic
    action within the central nervous system (8, 11, 15, 32,
    36). Thus acetaminophen would not be expected to
    interfere with muscle protein metabolism after exercise.

    ......However, long-term use of
    these drugs may inhibit the normal hypertrophic response
    to resistance training. Future studies on the
    impact of chronic consumption of over-the-counter
    doses of these drugs on skeletal muscle are warranted"

  3. #3
    CRUISECONTROL's Avatar
    CRUISECONTROL is offline Post Whore Extraordinaire Cruising On Autopilot
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    Quote Originally Posted by Dizz28 View Post
    "Neither drug had any influence on whole body protein breakdown, as
    measured by rate of phenylalanine appearance, on serum
    creatine kinase, or on rating of perceived muscle soreness
    compared with PLA. These results suggest that over-thecounter
    doses
    of both ibuprofen and acetaminophen suppress
    the protein synthesis
    response in skeletal muscle after eccentric
    resistance exercise

    Ibuprofen and acetaminophen are purported to relieve
    muscle soreness and pain through separate mechanisms.
    Ibuprofen is known to block cyclooxgenase (EC
    1.14.99.1), which then reduces metabolites produced by
    this enzyme, such as prostaglandins, that are at least
    partially responsible for inflammation and algesia (14,
    35, 36). However, prostaglandins have also been shown
    to regulate protein metabolism, and NSAIDs similar to
    ibuprofen have been shown to blunt protein metabolism
    in animal skeletal muscle (24, 30). Therefore,
    skeletal muscle protein metabolism may be influenced
    in individuals who consume ibuprofen after unaccustomed
    exercise. The mechanism of analgesic action of
    acetaminophen, also known as paracetamol, is less
    clear; however, it is believed to have its analgesic
    action within the central nervous system (8, 11, 15, 32,
    36). Thus acetaminophen would not be expected to
    interfere with muscle protein metabolism after exercise.

    ......However, long-term use of
    these drugs may inhibit the normal hypertrophic response
    to resistance training. Future studies on the
    impact of chronic consumption of over-the-counter
    doses of these drugs on skeletal muscle are warranted"

    Thanks very good info

  4. #4
    Ashop's Avatar
    Ashop is offline Anabolic Member
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    Quote Originally Posted by CRUISECONTROL View Post
    Do drugs such as anti inflamatory, muscle relaxers and other pain relievers while taken during cycle lessen cycle results????
    Ive heard and read conflicting reports going both ways. I would only use them if absolutley needed while on cycle.

  5. #5
    CRUISECONTROL's Avatar
    CRUISECONTROL is offline Post Whore Extraordinaire Cruising On Autopilot
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    Quote Originally Posted by ALIN View Post
    Ive heard and read conflicting reports going both ways. I would only use them if absolutley needed while on cycle.
    yeah I strained a muscle the other day and have been taking naproxen to help with the irritation

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