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Controlling Estradiol

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by , 02-14-2012 at 11:40 PM (1167 Views)
LEF Article:

Wow #1:

men with the highest blood levels of estradiol had a 2.2-fold greater risk of stroke compared with those whose estradiol levels were lower [...]

This study revealed that estradiol blood levels greater than 34.1 pg/mL resulted in this more than doubling of stroke incidence. Life Extension long ago warned men to keep their estradiol levels below 30 pg/mL


After multivariate adjustments, men with the greater estradiol concentration had a 1.78 times higher incidence of urinary tract symptoms. An even greater incidence of urinary tract symptoms occurred in men with the highest levels of a dihydrotestosterone metabolite, whereas blood testosterone level showed no effect on urinary tract symptoms. The doctors who conducted this study concluded by stating, “in this cross-sectional study representative of older US men, circulating AAG, a metabolite of dihydrotestosterone, and estradiol were associated with an increased risk of having lower urinary tract symptoms.”

Interesting tip!

It is not just excess estradiol that poses health risks. Specific estrogen metabolites may also initiate and promote hormone-related cancers. Daily consumption of cruciferous vegetables (broccoli, cauliflower, cabbage, Brussels sprouts),54-59 along with isoflavone-rich soy foods 60-64 converts these dangerous estrogen metabolites (such as 16-alpha-hydroxyestrone) to safe ones (2-hydroxyestrone) that may protect against prostate cancer.

Eat more broccoli!


men need estrogen to maintain bone density, cognitive function, and even to maintain the inner lining of the arterial wall (the endothelium)
We have recommended that ideal ranges for estradiol for most aging men are between 20 and 30 pg/mL of blood. Below 18 pg/mL increases osteoporosis risk, while levels greater than 30 pg/mL increase heart attack and stroke incidence.

How to high low estradiol:

[Lose belly fat]
"One of the most effective ways for men to reduce belly fat is to restore their free testosterone to youthful ranges. Nutrients that inhibit the aromatase enzyme can help boost testosterone levels by preventing its conversion (aromatization) into estradiol. "
For men with excess aromatase activity, this topically absorbed testosterone might convert into too much estradiol. If this happens, the use of very low-dose aromatase-inhibiting drugs (0.5 mg of Arimidex® twice a week) may be all that is needed to protect against estrogen overload. Some men don’t need these drugs and can use nutrient formulas that have aromatase-inhibiting properties.


  1. mikenj's Avatar
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    Now this is what I'm looking for. Thanks