
Originally Posted by
thegodfather
It's important to understand that in the medical world, Ethyl Oleate is only really used as a solvent in injectable progesterone therapy for women seeking to increase their chance at pregnancy. So, unfortunately, there is little documentation on the incidence and frequency of allergic reactions to Ethyl Oleate. It is also hard to pinpoint whether it is the solvent, preservatives, base compound, or impurities in all of the above.
There can be byproducts and unknown compounds (referred to as "peaks" on a GC/MS) that occur in the production process of hormones. That is for instance, why powders are labeled with certain purities, i.e.- 97%,98%,99%, etc. These various byproducts can be completely harmless, or they can cause rather unfavorable reactions in the human body, although their effects are more often than not negligible. However, there can be dangerous byproducts in the production of hormones and supplements, you can google Peak E and Peak X in the production of L-Tryptophan and the very serious incidences of undifferentiated fibromyalgia that was caused by these byproducts.
The concentration and ratios of Benzyl Alcohol and Benzyl Benzoate, used as a preservative in the injectable solution can also cause adverse reactions.
Additionally, the various solvents, also known as "carriers," can cause allergic reactions in some people. Ethyl Oleate, Polyethylene Glycol, Cottonseed Oil, Grapeseed oil, etc, and so on. It's important to understand also that in many human grade testosterone preparations the preservative chlorbutanol is used, which is actually a mild anesthetic and anti-bacterial.
So the situation BJJ, is that you have multiple variables which could all be causing your adverse drug reaction (ADR). There is also a distinction, when referring to the carriers/preservatives between technical grade and pharmacy grade. Many people on the forums seem to think that this is a distinct difference in the product itself or that the products are completely different. In fact it is not, pharmacy grade is simply, in this case, carriers/preservatives which are manufactured according to the United States Pharmacopoeia standards. Hence, this is where the acronym "USP" grade comes from. It must be manufactured to the standards of the United States Pharmacopoeia, it must be manufactured in a facility using good manufacturing processes, which is where the acronym "GMP" derives from.
Any number of impurities or contamination in any step of the manufacturing process in any one of the components that goes into making a sterile injectable solution can be the cause of your problem. However, if we, for arguments sake say they you are using 100% USP-NF drugs, in a GMP facility, then we could say you are most likely experiencing an anaphylactic rxn to the carrier/preservative. In this case, you should in addition to experiencing the diarrhea, experience inflammation at the injection site, adema, redness, etc. You may have to switch brands to one which does not use a more exotic carrier/preservative. In the meantime, to attenuate some of the symptoms you are experiencing, try taking 50-100mg of Diphenhydramine (brand name Benadryl) a day, and see if this helps. I would be quite worried if 4-6mg of Loperamide (brand name Immodium) was not attenuating the diarrhea. If the symptoms persist you should seek medical care immediately...
Good luck bro...