I don’t think AAS will have any direct effect on your venous situation unless you gain water weight, and then simply the volume in the veins in the lower extremities. I always feel much better when e2 is a little high (high normal or just above) and this comes with a bit of water weight but nothing horrible. You may want to monitor e2 to lower point but where you still feel good and so e2 isn’t low enough that you get sides from it.
Again, keep an eye on your blood count and stay in the normal range with donations as needed.
And since you mentioned venous reflux, here is an article summation on increased risk for DVT with venous reflux. But this has nothing to do with AAS, it’s simply related to your pre-existing condition.
https://www.ncbi.nlm.nih.gov/pubmed/26993861