I'm using 2.5 mgs a day of letro and am 1/2 way though my second bottle to try to reverse some gyno.
The size of my lump has improved but is still present, I plan on running it for awhile though.
I've read of people using it for a few weeks with no real help, but I think you have to run it for a long time for it to take the effect on the gyno.
The side effects of course are a lack of sex drive, and that just hit me about a month or so into this. If the sides don't surface until then I imagine the good side effects won't take effect for awhile either.
I've used Nova and it does help also, but it comes back. 20mgs 3times a day and in 30 days you won't even know you have it. But it comes right back after a few weeks of no Nova.