do you mean how long off clen before starting a cycle of gear? or you mean before starting clen again. There is no reason to wait to start a cycle of gear. As for starting clen again, never. Seriously though clen will downregulate your receptors so stoping for 2 weeks or taking benadryl is usually the rule of thumb. Personally I don't like clen and get minimal to zero benefits from it so I never use it.