There are a ton of these articles out there....pubmed it.
The % I read was some time ago and was high....the first article indicates as high a female orals contraceptives which is 99%.

I hope the best for you but if I was playing the odds???????

Also I remember reading that test transferred to the wife can cause birth defects such as unusual male genitalia in the child....premature sexual differentiation ect...



Anawalt BD, Amory JK.

VA Puget Sound Healthcare System, Department of Medicine, University of Washington, Seattle 98108, USA. [email protected]

As the world human population continues to explode, the need for effective, safe and convenient contraceptive methods escalates. Historically, women have borne the brunt of responsibility for contraception and family planning. Except for the condom, there are no easily reversible, male-based contraceptive options. Recent surveys have confirmed that the majority of men and women would consider using a hormonal male contraceptive if a safe, effective and convenient formulation were available. Investigators have sought to develop a male hormonal contraceptive based on the observation that spermatogenesis depends on stimulation by gonadotropins, follicle-stimulating hormone (FSH) and luteinising hormone (LH). Testosterone (T) and other hormones such as progestins suppress circulating gonadotropins and spermatogenesis and have been studied as potential male contraceptives. Results from two large, multi-centre trials demonstrated that high-dosage T conferred an overall contraceptive efficacy comparable to female oral contraceptives. This regimen was also fully reversible after discontinuation. However, this regimen was not universally effective and involved weekly im. injections that could be painful and inconvenient. In addition, the high dosage of T suppressed serum high-density lipoprotein (HDL) cholesterol levels, an effect that might increase atherogenesis. Investigators have attempted to develop a hormonal regimen that did not cause androgenic suppression of HDL cholesterol and that was uniformly effective by suppressing spermatogenesis to zero in all men. Studies of combination regimens of lower-dosage T and a progestin or a gonadotropin-releasing hormone analogue have demonstrated greater suppression of spermatogenesis than the WHO trials of high-dosage T but most of these regimens cause modest weight gain and suppression of serum HDL cholesterol levels. Overall, the data suggest that we are close to developing effective male hormonal contraceptives. The focus is now on developing effective oral regimens that could be safely taken daily or long-acting depot formulations of a male hormonal contraception that could be conveniently injected every 3 - 6 months. In this article, we shall review the exciting new developments in male hormonal contraception.

PMID: 11585019 [PubMed - indexed for MEDLINE]


Determinants of the Rate and Extent of Spermatogenic Suppression during Hormonal Male Contraception: An Integrated Analysis.
Liu PY, Swerdloff RS, Anawalt BD, Anderson RA, Bremner WJ, Elliesen J, Gu YQ, Kersemaekers WM, McLachlan RI, Meriggiola MC, Nieschlag E, Sitruk-Ware R, Vogelsong K, Wang XH, Wu FC, Zitzmann M, Handelsman DJ, Wang C.

Context: Male hormonal contraceptive methods require effective suppression of sperm output. Objective: To define the covariables that influence the rate and extent of suppression of spermatogenesis to a level shown in previous WHO sponsored studies to be sufficient for contraceptive purposes (</= 1 million/mL). Design: An integrated analysis of all published male hormonal contraceptive studies of at least 3 months treatment duration. Setting: De-identified individual subject data provided by investigators of 30 studies published between 1990-2006. Participants: 1756 healthy (by physical, blood and semen exam) men aged 18-51 years of predominately Caucasian (two-thirds) or Asian (one-third) descent. This represents about 85% of all the published data. Intervention(s): Men were treated with different preparations of testosterone, with or without various progestins. Main Outcome Measure: Semen analysis. Results: Progestin coadministration increased both the rate and extent of suppression. Caucasian men suppressed sperm output faster initially but ultimately to a less complete extent than did non-Caucasians. Younger age and lower initial blood testosterone or sperm concentration were also associated with faster suppression, but the independent effect sizes for age and baseline testicular function were relatively small. Conclusion: Male hormonal contraceptives can be practically applied to a wide range of men, but require coadministration of an androgen with a second agent (i.e progestin) for earlier and more complete suppression of sperm output. While considerable progress has been made toward defining clinically effective combinations, further optimization of androgen-progestin treatment regimens is still required.

PMID: 18303073 [PubMed - as supplied by publisher]