Free Diet advice by Narkissos & Novastepp: Intro to Performance Nutrition 101

[Narkissos]

Well I have more of an individual taste for amino acids as I buy them in bulk in the kilo

I recalled you saying that in the past

If you check out the BCCA one its says `You can increase the effectiveness of BCAAs by consuming 10mg of Vitamin B6 with every 10g of BCAA.` Is this valid mate?

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The b-complex vits, aside from being the 'stress complex' is primarily used for the release of energy from food...Correct?

Afterall... that's the primary reason i push the supplementation of the b-complex to all my clients.

Each individual b-vitamin has a specific role.

It just so happens that b6 is involved the transport of amino acids.

Digging through my references:

The first naturally occurring form of vitamin B-6 was isolated in 1938. It has the structure, confirmed by chemical synthesis (1939), of 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine (I; R = -CH2OH). The trivial name "pyridoxine", proposed for this compound by P. György, came into general use as a synonym for "vitamin B-6". Two other natural compounds possessing vitamin B-6 activity detected in 1944 and recognized as the aldehyde, or 4-formyl analogue (I; R = -CHO) of pyridoxine, and the corresponding amine, or 4-aminomethyl analogue (I; R = -CH2NH2), were designated "pyridoxal" and "pyridoxamine" respectively.

Note. The systematic name for I; R = -CH2OH, by IUPAC Organic Rule C-204.1, is 4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol.

Within the next few years, I. C. Gunsalus, E. E. Snell, A. E. Braunstein and others demonstrated that a phosphoric derivative of pyridoxal, later identified as pyridoxal 5'-phosphate (II; R = -CHO), is the coenzyme of a large group of specific enzymes catalysing reactions of amino-group transfer, decarboxylation and other metabolic transformations of individual amino acids. In the course of enzymic transamination, pyridoxal 5'-phosphate undergoes reversible conversion into pyridoxamine 5'-phosphate (II; R = -CH2NH2), which has coenzyme activity for the aminotransferases (EC 2.6.1.-), but not for other types of vitamin B-6-dependent enzymes

^^There are vitamin b-6-dependant enzymes involved in process(es) related to amino uptake and use.

Taking 10 mg of b6 with your BCAAs sounds like a plug for the sale of b6.

Personally I have my clients use 50-100mg of b-complex in multiple meals... So it isn't necessary to supplement b6 individually IMO.

Furthermore... the it would be more beneficial to supplement the entire complex imo.

-CNS




References:

Braunstein, A. E. (1960) in The Enzymes, 2nd edn (Boyer, P. D., Lardy, H. & Myrbäck, K., eds) p. 113, Academic Press, New York.

International Union of Pure and Applied Chemistry (1960) J. Am. Chem. Soc. 82, 5581.

"Nomenclature for Vitamins B-6 and Related Compounds" http://www.chem.qmul.ac.uk/iupac/misc/B6.html#r2

[Narkissos]

I recalled you saying that in the past



The b-complex vits, aside from being the 'stress complex' is primarily used for the release of energy from food...Correct?

Afterall... that's the primary reason i push the supplementation of the b-complex to all my clients.

Each individual b-vitamin has a specific role.

It just so happens that b6 is involved the transport of amino acids.

Digging through my references:



^^There are vitamin b-6-dependant enzymes involved in process(es) related to amino uptake and use.

Taking 10 mg of b6 with your BCAAs sounds like a plug for the sale of b6.

Personally I have my clients use 50-100mg of b-complex in multiple meals... So it isn't necessary to supplement b6 individually IMO.

Furthermore... the it would be more beneficial to supplement the entire complex imo.

-CNS




References:

Braunstein, A. E. (1960) in The Enzymes, 2nd edn (Boyer, P. D., Lardy, H. & Myrbäck, K., eds) p. 113, Academic Press, New York.

International Union of Pure and Applied Chemistry (1960) J. Am. Chem. Soc. 82, 5581.

"Nomenclature for Vitamins B-6 and Related Compounds" [[/url]

A brief but interesting intro to BCAA supplementation which i think everyone should read:



-CNS

[Merc..]

I recalled you saying that in the past



The b-complex vits, aside from being the 'stress complex' is primarily used for the release of energy from food...Correct?

Afterall... that's the primary reason i push the supplementation of the b-complex to all my clients.

Each individual b-vitamin has a specific role.

It just so happens that b6 is involved the transport of amino acids.

Digging through my references:



^^There are vitamin b-6-dependant enzymes involved in process(es) related to amino uptake and use.

Taking 10 mg of b6 with your BCAAs sounds like a plug for the sale of b6.

Personally I have my clients use 50-100mg of b-complex in multiple meals... So it isn't necessary to supplement b6 individually IMO.

Furthermore... the it would be more beneficial to supplement the entire complex imo.

-CNS




References:

Braunstein, A. E. (1960) in The Enzymes, 2nd edn (Boyer, P. D., Lardy, H. & Myrbäck, K., eds) p. 113, Academic Press, New York.

International Union of Pure and Applied Chemistry (1960) J. Am. Chem. Soc. 82, 5581.

"Nomenclature for Vitamins B-6 and Related Compounds" http://www.chem.qmul.ac.uk/iupac/misc/B6.html#r2

B6 hinders your gains .. see this thread .. See A-Robs post about it ( post #43).. He suggest only getting about the RDA amount .. I just wanted to point this out about b-6 as I know peeps that take huge amounts of it ..

http://forums.steroid.com/showthread...=hinders+gains

Merc.