DNP ?'s- Women, Cataracts, etc...

[Nstart]

GixxerChick, I think what ChuckLee is primarily trying to is discourage you from using DNP. There is a reason a lot of professional bodybuilders won't even touch the stuff.

At the end of the day it all really comes to diet and cardio. If you really must take something, then do a mild cycle of T3 and Clen (but I don't even recommend that).

To answer you question, I looked into DNP a while back and as far as I could find, all human research in regards to DNP has not occurred in many years. The reason being is that is just so dangerous that the few I have been able to find in medical libraries usually had to be stopped to due patients having to be hospitalized.

If electron transport doesn't produce ATP, then much more sugar must be metabolized for energy needs. Very low production of ATP would be lethal. In oxidative phosphorylation, the flow of electrons from NADH and FADH2 to oxygen results in the pumping of H+ from the matrix to the inner membrane space. This gradient of H+ can produce ATP by flowing through ATP synthetase in the mitochondrial inner membrane. Dinitrophenol disrupts the H+ gradient reducing ATP synthesis. Under these conditions, much of our food that we eat could not be used for ATP synthesis are we lose weight. However, too much inhibitor and we could make too little ATP for life. The difference between weight loss and death is only a small concentration change in dinitrophenol, making the drug dangerous.

There is also an article in JAMA (Journal of the American Medical Association) that did a trial with lab rats. Several rats died after being given dosages for 2 weeks, and even after the experiment stopped, all the rats died prematurely. They talked about it being difficult to directly relate the numerous DNP deaths of the 1940s because there were so many variables to it and that they strongly urge human trial of DNP be discontinued completely. When dealing with humans in an uncontrolled environment, it's almost impossible to say X person took Y drug 15 years ago and as a result is now having problems with Z.

When I return to work on Monday, I'll find the article and send it to you.

[GixxerChick]

GixxerChick, I think what ChuckLee is primarily trying to is discourage you from using DNP.

Whether or not I plan to use it does not affect the answers to the questions I posted. I don't understand why I can't seek unbiased information without a personal judgement. I think its a shame to discourage any attempt at expanding one's knowledge, especially when so few people even bother to research things as deeply as I have.

No, I do not plan on using DNP due to the inherent risk that seems even greater in women, but it does not mean I am not extremely interested in exploring it a little deeper. I have a published paper myself in the field of neuropsychopharmacology, so obviously I'm intelligent enough to come to my own conclusions. I didn't ask for opinions on whether or not you feel I personally should take DNP, I asked for answers to objective questions hoping someone here might have researched it a little longer and more thoroughly than I have.

I'll see if I can find the answers on my own since people here are clearly unwilling to help under the guise of protecting me. It seems the pursuit of knowledge is looked down upon moreso than actually taking the chemical itself.