I wish a mod would post a sticky on this. Sust can be shot 1 x /10 days @ 250 with good results. I use 1x400@1 /wk with great results. No blood disorders, great gains, no flu... take it for what it's worth, but don't say that sust has to be shot eod at higher doses. Maybe if you are a giant muscle like arnold used to be. I', 5'11 185 and pretty lean...so it works for me this way