/nod gotta agree with most of your reply however I'm not quite sure about what you said:
As you get bigger the stress you put on your body becomes more pronounced. Lifting 315lbs for 10 puts more stress on your entire system than when you did 135lbs for 10.
Seems to me that 135lbs as a beginner would put just as much stress, if not more, on your system then lifting 315 as a more experienced lifter. The amount of stress would be relative to your strenth ie. if you take someone that can only lift 135 versus someone that can lift 315, the "amount" of stress produced would be the same as each person is lifting (to them) a lot of weight. It almost seems to be the complete opposite: as you gain experience lifting, your body theorectically learns to tolerate the stress more than when you first start out. Of course this doesn't take into account that as you begin lifting you aren't actually building muscle but instead are acclimating your system to lifting. I guess then you also have to take into account limiting factors like strength of tendons/stabilizing muscles/etc. I guess what I'm trying to say that going "balls to the wall" as a relatively inexperienced lifter wouldn't seem to produce that much less stress than going "balls to the wall" as an experienced lifter.

As far as allowing different muscles varying rest times I think you are right on. I've also read Hatfield's: Harcore Bodybuilding, A Scientific Approach. Some of his workout routines however seem to be a bit extreme. Just wondering if you have ever tried any of his routines and if so did you experience good results? Maybe I'm wrong but wouldn't the volume of training that he advocates put one in danger of seriously overtraining (perhaps not specific muscles but overall as the is so much volume on training days)?