Gyno Started

[Swifto]

The use of Letro helps the PgR by reducing concentrations of the PgR and estrogen receptors and lowering estrogen levels. Tren and deca do not aromatize into prog but act on the prog receptor. Deca binds at the rate of 20% and tren is 60% so using letro will give the deca/tren less prog receptors to bind too. Thats what i ment when i said Letro will help control progesterone issues.

Now i will say, the best way to prevent or decrease prolactin/progestrone induced gyno is by taking an anti-prolatin such as Caber or Bromo.

But like i mentioned, Letrozole does have anti-progestinic (not prolactin) properties.

Again though, this is mostly from my research into this topic. For all i know, i may be inaccruate. Unfortunately, im not the most knowledgeable member concerning this issue, however, i feel i have a basic understanding.

Ill PM someone i know will have some better insight for us. Hopefully he'll get back to me soon.

Hello hello...What have we here...



Lower E and PgR should also lower.

Tamox upregulates the PgR.

Reduce PgR by using RU-486/Mifepristone.

There are studies that show a decrease in the PgR from Letro. But it has no direct affinity for the PGR. But I'm not completely happy with it IMHO. It may be from a reduction in estrogen and the study is on cancer patients with breast tissue growth, not normal, healthy individuals. Thats a big difference IMHO. The patients arnt on steroids, they arnt exogenously administering steroids, that also changes things. There also not using progestins. I'm not happy with it.

Tamox lowers the effectiveness of type II AI's. Its roghly 40%.

There arnt any ACTUAL studies confirming it. But I've spoken to a doctor that states his patients experience increased levels of PRL from Testosterone. So taking a dopamine agonist is a good idea IMHO. Although I'm still not 100%...

PRL will also increase with HGH and IGF-1 use.

Vit-B6 is a good way of reducing PRL. But too much can damage your CNS and it will reduce androgen gene transcription. So there's a flip side.

Few points, but most have been said.

I think the prblem is estrogen. Not PgR or PRL. Estorgen is the hormone that causes ductal and glandular growth of the breast. Some argue PgR makes it worse, it may, but in primates studies show it doesnt.

[Juice Authority]

Hello hello...What have we here...



Lower E and PgR should also lower.

Tamox upregulates the PgR.

Reduce PgR by using RU-486/Mifepristone.

There are studies that show a decrease in the PgR from Letro. But it has no direct affinity for the PGR. But I'm not completely happy with it IMHO. It may be from a reduction in estrogen and the study is on cancer patients with breast tissue growth, not normal, healthy individuals. Thats a big difference IMHO. The patients arnt on steroids, they arnt exogenously administering steroids, that also changes things. There also not using progestins. I'm not happy with it.

Tamox lowers the effectiveness of type II AI's. Its roghly 40%.

There arnt any ACTUAL studies confirming it. But I've spoken to a doctor that states his patients experience increased levels of PRL from Testosterone. So taking a dopamine agonist is a good idea IMHO. Although I'm still not 100%...

PRL will also increase with HGH and IGF-1 use.

Vit-B6 is a good way of reducing PRL. But too much can damage your CNS and it will reduce androgen gene transcription. So there's a flip side.

Few points, but most have been said.

I think the prblem is estrogen. Not PgR or PRL. Estorgen is the hormone that causes ductal and glandular growth of the breast. Some argue PgR makes it worse, it may, but in primates studies show it doesnt.

Good stuff. I agree on estrogen being the culprit here.