Anavar FAQ - A great read.

[BJJ]

Maybe this thread is too old but I have a question that I haven't seen addressed elsewhere. According to this study (http://www.blackwell-synergy.com/doi...01-1-1150928.x), anavar can greatly decrease shbg levels. What exactly does shbg do? Should I be concerned about this? I tried to do a little research but I couldn't turn up much information other than that low shgb levels are a possible indicator of diabetes. Any insight would be helpful. Thanks.

Your link is about young guys on puberty while I believe any aas should not be used if your biological age is under 25yo. So, your reported study, do not apply.
In any case:

SHBG: Glycoprotein with high affinity for testosterone and estradiol, it is a protein of transport that conveys the steroidal hormones in the bloodstream to the target tissues.

After it was produced in the cells of testicular Leydig, under the influence of pituitary hormone LH (luteinising), the testosterone enter the stream circulatory where special binds to plasma proteins. Thanks to this link the testosterone may be transported to the various tissues where explains its own functions. In the blood of man the 45% of testosterone is linked with the SHBG (sex hormon binding protein), while the 53% is linked with the albumin (this protein has an affinity for the testosterone 1000 times lower than the SHBG but its blood concentration is 1000 times higher). Only 2% of testosterone ttl in man can migrate to the cells and exercise specific functions. The level of SHBG in the body varies from individual to individual and may be altered by many factors. An increased level of estrogen and thyroid hormones is associated with an increased concentration of SHBG and vice versa. The recruitment of anabolic steroids with high androgenic sides are associated with a decline of levels of SHBG.
The link of testosterone with the SHBG protects from a fast metabolism by ensuring blood concentration more stable and maintaining unchanged until reaching the target tissues. In the membranes plasma sensitive cells to its action were recently discovered specific receptors for the SHBG. In the light of these discoveries these carriers not acting only as mere carriers but hold a more complex that has yet to be clarified.
Anabolic steroids have different affinity for the SHBG. For some this feature is marked for other less. Some of them, as the proviron, are used for their strong tendency to bind with these proteins. This feature, apparently disadvantage, can become particularly useful if you are using at the same time other anabolic steroids.

[elpropiotorvic]

Your link is about young guys on puberty while I believe any aas should not be used if your biological age is under 25yo. So, your reported study, do not apply.
In any case:

SHBG: Glycoprotein with high affinity for testosterone and estradiol, it is a protein of transport that conveys the steroidal hormones in the bloodstream to the target tissues.

After it was produced in the cells of testicular Leydig, under the influence of pituitary hormone LH (luteinising), the testosterone enter the stream circulatory where special binds to plasma proteins. Thanks to this link the testosterone may be transported to the various tissues where explains its own functions. In the blood of man the 45% of testosterone is linked with the SHBG (sex hormon binding protein), while the 53% is linked with the albumin (this protein has an affinity for the testosterone 1000 times lower than the SHBG but its blood concentration is 1000 times higher). Only 2% of testosterone ttl in man can migrate to the cells and exercise specific functions. The level of SHBG in the body varies from individual to individual and may be altered by many factors. An increased level of estrogen and thyroid hormones is associated with an increased concentration of SHBG and vice versa. The recruitment of anabolic steroids with high androgenic sides are associated with a decline of levels of SHBG.
The link of testosterone with the SHBG protects from a fast metabolism by ensuring blood concentration more stable and maintaining unchanged until reaching the target tissues. In the membranes plasma sensitive cells to its action were recently discovered specific receptors for the SHBG. In the light of these discoveries these carriers not acting only as mere carriers but hold a more complex that has yet to be clarified.
Anabolic steroids have different affinity for the SHBG. For some this feature is marked for other less. Some of them, as the proviron, are used for their strong tendency to bind with these proteins. This feature, apparently disadvantage, can become particularly useful if you are using at the same time other anabolic steroids.

I might be wrong Bjj but aren't the studies that support that var is HPTA suppresive done on teenagers as well?...