the benedryl(diphenhydramine) myth has been debunked already, but you can run it straight through with ketotifen fumarate
btw, unless you know you can handle 100mcg as a starting dose i would start at 40mcg and increase by 20mcg every couple days so you can monitor the sides
remember, if your waking temp. increases 0.5-1.0 degree then the clen is working (if you don't know how to figure your waking temp i'll explain)