
Originally Posted by
RED26
Acetaminophen reduces inflammation via inhibition of PGF's (Prostaglandins) If you're not familiar with the term, to not complicate your life to much, let's put it this way:
1.- Weight training triggers the release of arachidonic acid.
2.- Arachidonic acid (the guilty one of your soreness) triggers inflamation via prostaglandins
3.- Prostaglandins are highly related to growth hormone's such as MGF (mecano growth factor) and IGF-1 (Insulin-like growth factor), then, those to HGH... And that means at high term muscle gain.
If you interrupt this whole process by taking NSAID's, forget about your training induced muscle growth AT LEAST for that day.
It depends on the dose for sure... But if you're not dying in agony of pain, why bother and sabotage your daily hard work in the gym?
Use it only when it's REALLY necessary. And if you're going to hurt your progress already, at least make it count and take something stronger. As it would be diclofenac sodium via I.M or I.V or simply hidrocodone... If you get it.