No "boosting" with this stuff. It's purpose and design is to reduce E2 and keep it in check. If your E2 is in the normal range, then there's no need to take it. However, that's why I believe (IMO) that when someone starts TRT, they should run BW 6 weeks after their first injection, then run quarterly BW labs thereafter. This is where you will know if you need to add/reduce the AI's.