Ok 4th week into it and....

[Jupiter2]

Just a guess on my part as I am no expert at either TRT or Bi-Polar Disorder but it does sound to me as though elevated estrogen might be your issue (Water gain is a by product of increased estrogen)

You might also want to discuss with your doctor different anti-D's. Wellbutrin is effective and is known to affect libido positively but I don't know if would be as helpful as Zoloft with regard to Bi-Polar Disorder.

Also, even though Test Cyp has a pretty long half life you will still experience Test levels that are higher a couple of days following your injection and lower just prior to your next scheduled dose. It makes sense to me that your disorder might make you more susceptible to mood swings as a result of the peaks and valleys associated with the therapy. If that is the case it might be helpful to flatten out those high's and low's a bit by injecting 50 mg's 2x per week or every 3 or 4 days instead of the 100mg's once every 7 days as you are doing now.

[highnmighty]

Just a guess on my part as I am no expert at either TRT or Bi-Polar Disorder but it does sound to me as though elevated estrogen might be your issue (Water gain is a by product of increased estrogen)

You might also want to discuss with your doctor different anti-D's. Wellbutrin is effective and is known to affect libido positively but I don't know if would be as helpful as Zoloft with regard to Bi-Polar Disorder.

Also, even though Test Cyp has a pretty long half life you will still experience Test levels that are higher a couple of days following your injection and lower just prior to your next scheduled dose. It makes sense to me that your disorder might make you more susceptible to mood swings as a result of the peaks and valleys associated with the therapy. If that is the case it might be helpful to flatten out those high's and low's a bit by injecting 50 mg's 2x per week or every 3 or 4 days instead of the 100mg's once every 7 days as you are doing now.

I have tried every AD there is and in regards to Wellbutrin its not suitable for me. You do make a good point about the peak & troughs of Test. I was thinking of running 80 - 100mgs E5D instead of 7. I was actually asking a couple of people on this forum who are doing this exact regimen and they say it works great for them. I most likely will start this in a couple of weeks. My question would be do I run 80mgs E5D or 100mg? Also with regards to E2 how much adex should one run at these dosages?