There is a amazing difference just between 200mg and 300mg weekley injections. You will make gains in the gym the first week you increase and make gains for a couple weeks. When the gains stop, just back off to your TRT dose and cruise for a while. You will keep your gains and give your body time to get the important tendons and ligaments time to adjust to the new muscle and will avoid injury. In a couple months bump her up again until gains stop. I have done blood work everytime and blood lipids, sugar, psa never gets worse and most of the time will improve a little.